Joe Baur: Aging, Metabolism, Caloric Restriction, NAD, Resveratrol, Rapamycin, Sirtuins, Longer Life
Updated: Apr 1
About the Guest: Joe Baur, PhD runs a research lab at the University of Pennsylvania studies the molecular mechanisms of aging and metabolism.
Episode Summary: Nick and Dr. Baur touch on a range of topics: aging as a passive vs. regulated process; mechanisms of aging (DNA mutations, oxidative stress, etc.); NAD and its role in normal physiology; the biology of sirtuins; rapamycin as an immunosuppressant & modulator of aging; the effects of diet & caloric restriction on aging; the potential slowing and